Mean ratios of concentration measures for zolpidem, fluoxetine, and norfluoxetine administered alone or in combination
| Zolpidem Parameter | Day 28 | Day 32 |
|---|---|---|
| AUC0–24 (ng·hr/ml) | ||
| Ratio | 0.977 | 1.036 |
| 95% CI4-a | 0.854–1.113 | 0.900–1.189 |
| C max(ng/ml) | ||
| Ratio | 1.027 | 1.043 |
| 95% CI | 0.937–1.123 | 0.954–1.136 |
| Fluoxetine/norfluoxetine Parameter | Fluoxetine | Norfluoxetine |
|---|---|---|
| AUC0–24(ng·hr/ml) | ||
| Ratio | 1.028 | 1.023 |
| 95% CI | 0.974–1.091 | 0.983–1.065 |
| C max (ng/ml) | ||
| Ratio | 1.018 | 1.038 |
| 95% CI | 0.956–1.091 | 0.985–1.093 |
| C 24 (ng/ml) | ||
| Ratio | 0.976 | 0.967 |
| 95% CI | 0.903–1.067 | 0.904–1.031 |
↵4-a CI, confidence interval.