Table 1

Urinary excretion of 2,2-dichloro-2-fluoroethyl glucuronide in human subjects exposed to HCFC-141b

Exposure Concentration	Sample Time	Individual Subjects’ Excretion		Average
Exposure Concentration	Sample Time	AG	EB	Average	LA	MO	RG	RH	WS	YK^1-a	XY^1-a
ppm	hr	nmol/mg creatinine		mean ± SD
250	Control	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
	0–4	0.92	1.03	0.85	0.70	1.93	0.88	1.18	1.26	0.83	1.06 ± 0.37
	4–12	SL^1-b	1.16	1.13	1.30	2.07	1.65	1.59	1.33	2.09	1.54 ± 0.38
	12–24	0.20	0.59	0.43	0.56	0.48	0.27	0.31	0.40	0.56	0.42 ± 0.14
500	Control	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
	0–4	1.36	1.94	2.42	2.49	1.67	3.06	1.25	3.18		2.17 ± 0.74
	4–12	6.77	3.03	2.85	2.28	1.06	3.01	2.72	3.34		3.17 ± 1.63
	12–24	0.26	0.85	0.81	1.00	0.74	0.76	0.47	1.41		0.79 ± 0.34
1000	Control	0.0	0.0	0.0	0.0	0.0	0.0	0.0
	0–4	0.95	1.32	6.08	3.61	4.46	5.04	3.06			3.50 ± 1.89
	4–12	10.38	0.84	5.69	5.17	4.32	5.71	4.40			5.22 ± 2.82
	12–24	0.54	0.43	1.40	2.05	0.82	2.24	1.52			1.29 ± 0.72