Metabolite profiles in mouse plasma and liver extracts after oral administration of 2 mg/kg cerivastatin2-a
| Metabolite (%)2-b | Sampling Time (hr) | |||
|---|---|---|---|---|
| Plasma | Liver | |||
| 0.5 | 4 | 0.5 | 4 | |
| Cerivastatin | —2-c | — | — | — |
| M-15 | — | 2.6 | 2.1 | 3.2 |
| M-16 | — | 2.5 | 5.5 | 7.0 |
| M-18 | — | — | 3.3 | — |
| M-19 | — | 0.3 | 3.0 | 2.5 |
| M-21 | — | 7.2 | 2.3 | 6.2 |
| M-25 | — | 1.9 | 8.5 | 8.2 |
| M-26 | — | — | 2.6 | 2.2 |
| M-27 | 54.7 | 21.3 | 18.9 | 5.3 |
| M-28 | 35.7 | 41.0 | 30.2 | 29.5 |
| M-30 | — | — | 1.0 | — |