Model | Human A-Type PON | Rabbit PON | ||||
---|---|---|---|---|---|---|
Kd1 | Kd2 | R2 | Kd1 | Kd2 | R2 | |
μM | μM | μM | μM | |||
Two independent sites-Bmax 1-a | 0.670 ± 0.050 | 122 ± 43.3 | 0.998 | 0.045 ± 0.007 | 19.00 ± 10.2 | 0.967 |
Two independent sites1-b | 0.384 ± 0.099 | 6.22 ± 1.24 | 0.969 | 0.014 ± 0.005 | 5.31 ± 0.94 | 0.900 |
Stepwise equilibrium1-c | 0.362 ± 0.086 | 6.60 ± 1.20 | 0.969 | 0.014 ± 0.005 | 5.33 ± 0.94 | 0.900 |
Stepwise-Bmax 1-d | 0.667 ± 0.050 | 124 ± 19.5 | 0.998 | 0.052 ± 0.006 | 115 ± 27.7 | 0.958 |
All values are expressed as the estimates ± SE at 95% confidence intervals by the GraphPad software.
↵1-a Eq. 1 was used to analyze the data. For human A PON, Bmax1 was 1.52 ± 0.04, and Bmax2 was 1.51 ± 0.23. For rabbit PON, Bmax1 was 1.32 ± 0.05, and Bmax2 was 0.69 ± 0.10.
↵1-b Eq. 2 was used to analyze the data.
↵1-c Eq. 3 was used to analyze the data.
↵1-d Eq. 4 was used to analyze the data. Bmax for human A PON was 1.52 ± 0.03; Bmax for rabbit was 1.40 ± 0.03.