Table 2
AUC in vitreous and retina after intravitreal injection of ISIS 2922
Dose
AUC
Vitreous
Retina
ISIS 2922
Total Oligonucleotide
ISIS 2922
Total Oligonucleotide
μg
μM-hr
2-a
11
34
50
12
31
57
178
240
67
190
115
350
449
124
518
↵
2-a
μM-hr = ((μg/7122)/kg)-hr.