Table 4

Major radioactive components expressed as percent of radioactivity chromatogram in 0–24-hr mouse fecal extracts after a 200 mg/kg oral dose of [14C]AT on days 1 and 14 of a multiple-dose study

DayApproximate Retention TimesTotal
33.54-a50.463.463.64-b68.5704-c8183.586.487.187.789.489.94-d90.991.8
min
11.224.431.0221.40.7017.612.71.382.234.505.172.093.6178.1
140.480.924.851.6215.51.447.009.941.101.923.539.334.865.626.3274.4
  • 4-a para-hydroxy AT.

  • 4-b ortho-hydroxy AT.

  • 4-c AT.

  • 4-d β-Oxidized AT.