Table 1

Rate of production of 3MI metabolites by pig liver microsomes

MetaboliteRate of Production ± S.D.MinimumMaximum
pmol/mg protein/min
UV-1750.7  ± 414.5180.51556.3
3MOI420.9  ± 118.1234.4700.8
HMOI272.4  ± 91.6118.9516.5
6-OH-3-Methylindole58.4  ± 47.2n.d.1-a 213.7
I3C37.1  ± 15.812.185.7
2-Aminoacetophenone7.8  ± 2.43.412.7
5-OH-3-methylindole5.1  ± 5.80.727.3
  • n = 30.

  • 1-a n.d., not detected.