Table 2

Extraction ratios in in situ IPIL

Perfusion periodIntestineLiverIntestineLiverIntestineLiver
0.4 μg/ml 3.5 μg/ml 20 μg/ml
10.0770.064  (1)2-a 0.0960.113  (3)0.0900.051  (5)
0.0710.131  (2)0.0720.152  (4)0.1030.112  (6)
30.0500.097  (3)0.0610.124  (1)0.0730.110  (2)
0.0840.059  (5)0.0950.142  (6)0.0820.102  (4)
  • 2-a Numbers in parentheses indicate individual rats. For example, rat 1 received 0.4 μg/ml 6AC in perfusion period 1 and 3.5 μg/ml in perfusion period 3.