Percentage of metabolites excreted into urine at 96 h after administration of [14C]1-NN
| Metabolite | HPLC RT2-a | Peak Identification2-b | % of Total Dose in Urine | |
|---|---|---|---|---|
| i.p. | i.v. | |||
| min | 100 mg/kg | 10 mg/kg | ||
| Dihydroxy-1-nitro-dihydronaphthalene-O-glucuronide | 19 | A | 2.4 | 3.1 |
| Hydroxy-1-nitronaphthalene-O-glucuronide | 21 | B | 3.0 | 5.0 |
| Dihydroxy-1-nitro-dihydronaphthalene-O-sulfate | 25 | C | 5.3 | 3.1 |
| N-acetyl-S-(hydroxy-1-nitro-dihydronaphthalene)-l-cysteine | 29 | D | 29.6 | 16.6 |
| Hydroxy-1-nitronaphthalene | 31 | E | 0.1 | 2.9 |
| Dihydroxy-1-nitronaphthalene | 37 | F | 4.1 | 9.0 |
| 1-Naphthylamine | 44 | G | 1.3 | 0.4 |
| Dihydroxy-1-nitro-dihydronaphthalene | 48 | H | 0.5 | 2.2 |
| 1-Nitronaphthalene | 51 | I | 6.9 | 2.1 |
| Other2-c | 7.4 | 12.0 | ||
| Total Dose in Urine (0–96 h) | 60.5% | 56.4% | ||