Table 1

Busulfan Cl/F determined in children 0 to 4, 5 to 8, and 9 to 16 y.o.

Busulfan Cl/FAge Category, years
0 to 45 to 89 to 16
N 682542
ml/min/kg AIBW6.77  ± 2.681-a 5.14  ± 2.451-b 3.45  ± 0.601-c
ml/min/m2 144  ± 521-a 131  ± 61111  ± 17

Cl/F values are expressed as mean ± S.D.

  • ↵1-a Children ages 0 to 4 versus 9 to 16, p< .05.

  • ↵1-b Children ages 0 to 4 versus 5 to 8, p < .05.

  • ↵1-c Children ages 5 to 8 versus 9 to 16, p < .05.