Table 2
Significance of ERMBT and intestinal P-gp in cyclosporin A C
max
and oral clearance
Variable
Probability (
p
value)
Contribution to Model
C
max
ERMBT
.0002
32%
P-gp/villin
.0024
31%
Oral clearance
ERMBT
<.0001
56%
P-gp/villin
.0059
17%