Liver Microsomes | KM | Vmax |
---|---|---|
μM | nmol/mg/min | |
Male | 53 ± 5 | 0.8 ± 0.0 |
Female | 70 ± 16 | 5.0 ± 0.6 |
Male treated with PB | 90 ± 16 | 2.8 ± 0.3 |
Female treated with PB | 102 ± 25 | 5.7 ± 0.8 |
Incubations were performed with 0.5 mg/ml microsomal protein for 30 min at an eprinomectin concentration ranging from 8 μM to 100 μM. Results are means ± S.D.