Table 3

Mean (± S.D.) amount of 2-AP recovered from plasma (μg/ml) or tissue (μg/g), and tissue-to-plasma (T/P) ratio at 30 min after 1-min i.v. infusion of the drug, 10 mg/kg body weight, to rats (N = 5)

Tissues2-APT/P
μg/ml plasma or μg/g tissue
Plasma1.64  ± 0.9251.00
Liver7.13  ± 2.695.24  ± 2.17
Lung0.260  ± 0.1460.160  ± 0.0353
Heart2.82  ± 1.411.85  ± 0.381
Brain2.95  ± 1.461.99  ± 0.575
Kidney8.70  ± 4.705.67  ± 2.03
Stomach3.71  ± 0.9953.30  ± 2.83
Small intestine3.35  ± 1.532.25  ± 0.499
Large intestine6.23  ± 2.924.24  ± 1.39
Spleen3.43  ± 1.902.03  ± 0.353
Muscle2.12  ± 0.9981.36  ± 0.197
Fat4.31  ± 2.453.03  ± 0.979