Hepatocyte Population | Km | Vmax | Pdiff |
---|---|---|---|
μM | nmol/min/mg protein | μl/min/mg protein | |
Regular (n = 6) | 26 ± 8.3 | 1.8 ± 0.26 | 3.2 ± 1.0 |
Periportal (n = 8) | 24 ± 13 | 1.8 ± 0.46 | 2.5 ± 1.1 |
Perivenous (n= 8) | 24 ± 9.1 | 1.8 ± 0.36 | 2.7 ± 0.9 |
↵2-a Best fitted to eq. 2; a weighting of 1/prediction was optimal.