Treatment | Parameters | |||||
---|---|---|---|---|---|---|
AST | ALT | AP | CsA | B.Wt. | Liver Weight | |
U/l | U/l | U/l | ng/l | g | g/100 g b.wt. | |
Control | 95 ± 4 | 30 ± 3 | 295 ± 24 | N/D | 269 ± 7 | 4.03 ± 0.12 |
CsA | 87 ± 4 | 27 ± 4 | 282 ± 16 | 727 ± 77 | 253 ± 6 | 4.10 ± 0.14 |
p | N.S. | N.S. | N.S. | — | N.S. | N.S. |
Animals received CsA (3.33 mg/kg/day × 10 days) or olive oil (control). AST, ALT, and AP were determined in fresh serum while Ca2+ and CsA were analyzed in whole blood of sham-operated animals. n = 8/group except for CsA determination, where n = 3. N/D indicates not detectable. Statistically significant differences between group means were evaluated by the Student’s t test.