Tissue distribution after i.p. administration of curcumin in mice
| Sample or Tissue | Curcumin | Total Curcumin | Organ or Plasma1-a |
|---|---|---|---|
| μg/g | μg/total organ | ||
| Plasma | 0.60 ± 0.031-a | 0.52 ± 0.03 | 0.86 ± 0.01 |
| Kidneys | 7.51 ± 0.08 | 3.00 ± 0.03 | 0.40 ± 0.07 |
| Spleen | 26.06 ± 1.06 | 2.61 ± 0.11 | 0.10 ± 0.01 |
| Liver | 26.90 ± 2.58 | 33.09 ± 3.17 | 1.23 ± 0.08 |
| Brain | 0.41 ± 0.01 | 0.18 ± 0.01 | 0.43 ± 0.04 |
| Intestine | 117.04 ± 6.86 | 319.52 ± 18.73 | 2.73 ± 0.27 |
Values are mean ± S.E.M. of five mice. Curcumin (0.1 g/kg) was administered i.p. to each mouse. Animals were killed 1 h after dosing.
↵1-a Organ weight is given in g. Plasma is given in ml.