Kinetic parameters for HC formation in microsomes from UT and ABT-, PB-, and βNF-treated rats
| Vmax | Km | CL | |||
|---|---|---|---|---|---|
| CL1 | CL2 | CLint | |||
| pmol/min/mg protein | μM | μl/min/mg protein | |||
| ABT | 1.2 ± 0.3** | 0.3 ± 0.2 | 5.9 ± 4.8* | 0.2 ± 0.1* | 6.2 ± 4.7** |
| PB | 112.7 ± 36.5* | 3.4 ± 0.6 | 32.6 ± 5.9 | 11.1 ± 5.2* | 43.7 ± 10.8 |
| βNF | 5027 ± 2063** | 11.1 ± 2.3** | 454 ± 169** | 13.0 ± 5.0* | 467 ± 171** |
| UT | 39.8 ± 9.8 | 0.9 ± 0.1 | 47.7 ± 17.4 | 2.1 ± 1.0 | 49.8 ± 18.6 |
Statistical difference from UT (* p < .05, ** p < .01).