Table 4

Excretion of radioactivity in the urine and feces after single oral administration of [¹⁴C]SKP-450 to rats

Time	% Dose
Time	Urine	Feces	Total
0–6 h	23.85 ± 6.88	0.17 ± 0.08	24.03 ± 5.90
6–12 h	28.51 ± 12.79	9.19 ± 4.48	37.70 ± 8.05
12–24 h	11.82 ± 2.57	14.55 ± 2.10	26.37 ± 3.26
24–48 h	2.29 ± 0.72	4.64 ± 1.44	6.93 ± 1.38
48–72 h	0.37 ± 0.10	1.64 ± 0.87	2.01 ± 0.83
72–96 h	0.14 ± 0.03	0.72 ± 0.62	0.86 ± 0.56
96–120 h	0.06 ± 0.01	0.15 ± 0.08	0.21 ± 0.07
120–144 h	0.03 ± 0.01	0.03 ± 0.01	0.06 ± 0.02
144–168 h	0.03 ± 0.01	0.02 ± 0.01	0.05 ± 0.02
Total	67.10 ± 14.29	31.11 ± 7.03	98.21 ± 2.31

4-150 Each value represents the relative percentage to total radioactivity administered.