Comparison of absorption parameters of CsA and SDZ-RAD after oral administration of either 2.5 mg/kg CsA or 0.6 mg/kg SDZ-RAD alone and as a coadministration
| Compounds | Cmax | AUC | |||
|---|---|---|---|---|---|
| CsA | RAD | CsA | RAD | ||
| ng/ml | ng · ml−1 · h | ||||
| CsA | 800 ± 146 | 410 ± 530 | |||
| RAD | 7 ± 2 | 43 ± 12 | |||
| CsA | RAD | 743 ± 88 | 34 ± 4 | 5020 ± 420 | 217 ± 30 |
Results are the mean ± S.E.M. of four samples.