Effect of different xanthates on the 7-EFC O-deethylation activity of P-450 2B6
| Xanthate | KI | kinactivation | T1/2 |
|---|---|---|---|
| μM | min−1 | min | |
| C3iso | 6.5 | 0.01 | 63 |
| C8 | 1.0 | 0.02 | 36 |
| D609 | 4.7 | 0.01 | 69 |
| C14 | 9.9 | 0.01 | 111 |
Assay conditions were as described in Experimental Procedures. The data shown represent the mean from three different experiments.