Proportion of each metabolite in bile 2-a | Cumulative recovery | |||
---|---|---|---|---|
VPA alone | PAPM treatment | VPA alone | PAPM treatment | |
TLC % | % of Dose | |||
VPA | 2.7 ± 1.2 2-b | 1.6 ± 1.0 | 1.1 ± 0.5 | 0.9 ± 0.6 |
BM-2 | 3.9 ± 0.6 | 4.2 ± 2.6 | 1.7 ± 0.3 | 2.4 ± 1.5 |
VPA glucuronide | 89.4 ± 1.5 | 90.6 ± 4.7 | 38.3 ± 0.7 | 52.5 ± 2.7 |
BM-1 | 2.9 ± 0.8 | 2.6 ± 0.6 | 1.3 ± 0.4 | 1.5 ± 0.4 |
n2-c | 3 | 5 | 3 | 5 |