Univariate correlation of 9-AC lactone and 9-AC total concentrations at each sample time point with the corresponding AUC in the training-data set
| Time Point | 9-AC Lactone | 9-AC Total | ||
|---|---|---|---|---|
| h | n | r | n | r |
| 0.33 | 14 | 0.389 | 17 | 0.241 |
| 0.67 | 19 | 0.733 | 20 | 0.571 |
| 1.0 | 20 | 0.854 | 20 | 0.628 |
| 1.5 | 20 | 0.849 | 20 | 0.754 |
| 2.0 | 20 | 0.841 | 20 | 0.862 |
| 3.0 | 20 | 0.959 | 20 | 0.989 |
| 5.0 | 20 | 0.921 | 20 | 0.943 |
| 7.5 | 19 | 0.717 | 20 | 0.943 |
| 11 | 19 | 0.699 | 20 | 0.931 |
| 24 | 12 | 0.514 | 19 | 0.899 |
Abbreviation: n, number of data sets with complete pharmacokinetic curves.