Microsomal CYP enzyme activities in freshly cut and 1-h cultured human liver slices
| Enzyme Activity1-a | No. of Livers | Liver Slice Microsomes1-b | |
|---|---|---|---|
| Freshly Cut | Cultured for 1 h | ||
| 7-EthoxyresorufinO-deethylase | 3 | 13.6 ± 7.5 | 13.0 ± 5.9 |
| Tolbutamide methylhydroxylase | 3 | 49.2 ± 26.6 | 51.0 ± 18.5 |
| Debrisoquine 4-hydroxylase | 3 | 19.4 ± 6.7 | 37.2 ± 16.7 |
| Testosterone 6β-hydroxylase | 4 | 356 ± 240 | 396 ± 265 |