Estimated levels of the five major isoforms in HLM pools
| Isoform | Mean | References |
|---|---|---|
| % | ||
| CYP1A2 | 13 | Shimada et al. (1994), Guengerich and Turvy (1991), Belloc et al. (1996) |
| CYP2C9 | 20 | Shimada et al. (1994), Becquemont et al. (1998),Wester et al. (2000), Inoue et al. (1997), Lasker et al. (1998) |
| CYP2C19 | 4 | Wester et al. (2000), Inoue et al. (1997),Lasker et al. (1998) |
| CYP2D6 | 2 | Shimada et al. (1994),Becquemont et al. (1998), Imaoka et al. (1996) |
| CYP3A4 | 30 | Shimada et al. (1994), Belloc et al. (1996),Becquemont et al. (1998) |
Mean total level = 320 pmol of CYP · mg−1 of microsomal protein.