Mean percentage contribution of individual CYPs to oxidative metabolism
| Compound | CYP1A2 | CYP2C9 | CYP2C19 | CYP2D6 | CYP3A4 | Literature |
|---|---|---|---|---|---|---|
| % | ||||||
| Tolbutamide | 70 | 30 | 2C | |||
| Diazepam | 100 | 2C19>3A | ||||
| Metoprolol | 100 | 2D6 | ||||
| Ibuprofen | 90 | 10 | 2C9 | |||
| Propranolol | 26 | 15 | 59 | 2D6, 1A2, 2C19 | ||
| Dextromethorphan | 14 | 86 | 2D6>3A | |||
| Omeprazole | 68 | 32 | 2C19≫3A | |||
| Diltiazem | 7 | 93 | 3A | |||
| Testosterone | 100 | 3A | ||||
| Verapamil | 100 | 3A | ||||