Table 1

Excretion of radioactivity in urine and feces after i.v. (3 mg) and oral (10 mg) administration of [14C]rizatriptan to humans

Subject% of Dose Excreted (0–120 h)
3 mg i.v.10 mg p.o.
UrineFecesTotalUrineFecesTotal
00191.53.394.864.612.977.5
00294.42.196.585.714.7100.4
00385.95.491.383.28.591.7
00489.15.294.386.712.599.2
00590.35.896.188.711.5100.2
00694.34.999.286.99.396.2
Mean90.94.595.482.611.694.2
S.D.3.21.42.69.02.38.8