Drug | Example of Clinical Use | Dosage/Day | Maximum M Dosage/Day | Fold Maximum Dose versus Maximum Dexamethasone Dose |
---|---|---|---|---|
Rifampicin | Staphylococcal infections | 0.6–1.2 g/day, oral | 1.5 mmol | 60 |
Tuberculosis | 2–4 divided doses | |||
Dexamethasone | Anti-inflammatory, Diagnosis of Cushing's disease | 0.5–10 mg/day, oral | 25 μmol | 1 |
Spironolactone | Edema and ascites in cirrhosis of the liver | 100–200 mg/day, oral | 480 μmol | 19 |
Congestive heart failure | ||||
Cyproterone acetate | Male hypersexuality | 200–30 mg/day, oral | 720 μmol | 29 |
Prostate cancer | 2–3 divided doses | |||
Metyrapone | Diagnosis and treatment of Cushing's disease | 0.25–6 g/day, oral | 27 mmol | 1080 |
6 divided doses |
Data taken from the British National Formulary 37 (March 1999), published by the British Medical Association.