Tissue | Sex | μg eq D4/g Tissue | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
0 h | 1 h | 3 h | 12 h | 24 h | 48 h | 72 h | 96 h | 120 h | 168 h | ||
7 ppm | |||||||||||
Plasma | M | 0.31 ± 0.03 | 0.34 ± 0.02 | 0.32 ± 0.03 | 0.09 ± 0.00 | 0.05 ± 0.00 | 0.03 ± 0.01 | 0.02 ± 0.003-b | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.00 |
F | 0.31 ± 0.04 | 0.28 ± 0.02 | 0.26 ± 0.01 | 0.09 ± 0.01 | 0.05 ± 0.00 | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.00 | |
Fat | M | 1.02 ± 0.123-b | 0.96 ± 0.58 | 1.52 ± 0.22 | 0.98 ± 0.29 | 1.24 ± 0.92 | 1.09 ± 1.02 | 0.67 ± 0.813-b | 0.48 ± 0.62 | 0.52 ± 0.41 | 0.35 ± 0.31 |
F | 1.94 ± 0.78 | 2.33 ± 0.82 | 2.28 ± 0.95 | 1.86 ± 0.48 | 2.04 ± 0.69 | 1.10 ± 0.37 | 1.16 ± 0.27 | 1.19 ± 0.35 | 1.09 ± 0.18 | 0.63 ± 0.15 | |
Liver | M | 1.12 ± 0.12 | 0.82 ± 0.06 | 0.75 ± 0.07 | 0.27 ± 0.02 | 0.21 ± 0.02 | 0.14 ± 0.02 | 0.10 ± 0.013-b | 0.08 ± 0.01 | 0.06 ± 0.01 | 0.05 ± 0.01 |
F | 1.26 ± 0.07 | 0.90 ± 0.03 | 0.65 ± 0.04 | 0.28 ± 0.01 | 0.21 ± 0.02 | 0.14 ± 0.02 | 0.11 ± 0.01 | 0.10 ± 0.01 | 0.08 ± 0.01 | 0.06 ± 0.00 | |
Lung | M | 1.68 ± 0.14 | 1.56 ± 0.13 | 1.25 ± 0.11 | 0.88 ± 0.06 | 0.64 ± 0.04 | 0.55 ± 0.03 | 0.50 ± 0.023-b | 0.42 ± 0.05 | 0.36 ± 0.03 | 0.42 ± 0.12 |
F | 1.70 ± 0.08 | 1.47 ± 0.06 | 1.10 ± 0.05 | 0.75 ± 0.07 | 0.58 ± 0.09 | 0.51 ± 0.02 | 0.51 ± 0.09 | 0.50 ± 0.01 | 0.45 ± 0.06 | 0.47 ± 0.03 | |
Ovary | F | 1.55 ± 0.39 | 1.20 ± 0.053-b | 0.75 ± 0.13 | 0.37 ± 0.07 | 0.19 ± 0.03 | 0.26 ± 0.093-b | 0.16 ± 0.09 | 0.15 ± 0.10 | 0.12 ± 0.05 | 0.10 ± 0.06 |
Uterus | F | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
Vagina | F | 0.60 ± 0.39 | 0.46 ± 0.05 | 1.26 ± 0.66 | 0.43 ± 0.21 | 0.27 ± 0.07 | 0.20 ± 0.07 | 0.19 ± 0.08 | 0.15 ± 0.12 | 0.06 ± 0.01 | 0.09 ± 0.03 |
Testes | M | 0.27 ± 0.02 | 0.28 ± 0.01 | 0.29 ± 0.01 | 0.09 ± 0.01 | 0.05 ± 0.00 | 0.03 ± 0.01 | 0.02 ± 0.003-b | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.02 ± 0.00 |
700 ppm | |||||||||||
Plasma | M | 25.27 ± 0.67 | 21.86 ± 2.09 | 22.04 ± 0.57 | 6.98 ± 0.38 | 4.13 ± 0.23 | 2.30 ± 0.12 | 2.00 ± 0.88 | 1.27 ± 0.08 | 0.85 ± 0.04 | 0.55 ± 0.04 |
F | 20.96 ± 1.13 | 18.34 ± 3.15 | 18.40 ± 1.34 | 5.78 ± 0.72 | 3.49 ± 0.13 | 1.97 ± 0.15 | 1.49 ± 0.17 | 1.05 ± 0.13 | 0.87 ± 0.07 | 0.65 ± 0.05 | |
Fat | M | 138.37 ± 18.72 | 93.52 ± 32.17 | 111.25 ± 13.10 | 112.47 ± 10.66 | 91.07 ± 20.04 | 94.95 ± 25.41 | 56.87 ± 7.16 | 63.17 ± 8.23 | 57.20 ± 6.12 | 45.95 ± 6.44 |
F | 158.51 ± 20.84 | 179.38 ± 76.81 | 189.48 ± 31.85 | 165.12 ± 33.42 | 167.91 ± 32.86 | 122.71 ± 27.08 | 121.29 ± 30.90 | 90.12 ± 15.31 | 96.94 ± 12.82 | 70.89 ± 10.82 | |
Liver | M | 115.17 ± 3.35 | 63.44 ± 3.46 | 48.14 ± 1.06 | 23.20 ± 0.79 | 17.82 ± 1.08 | 12.57 ± 0.99 | 8.42 ± 0.53 | 7.63 ± 0.34 | 6.06 ± 0.51 | 4.27 ± 0.30 |
F | 129.39 ± 7.30 | 78.64 ± 7.84 | 47.90 ± 2.60 | 21.15 ± 2.63 | 16.21 ± 1.12 | 11.21 ± 0.88 | 9.12 ± 0.67 | 7.35 ± 1.02 | 6.44 ± 0.22 | 4.53 ± 0.55 | |
Lung | M | 193.42 ± 27.95 | 127.81 ± 20.35 | 102.71 ± 6.31 | 74.72 ± 14.22 | 60.94 ± 6.16 | 57.59 ± 8.29 | 44.38 ± 3.23 | 42.15 ± 4.90 | 41.74 ± 1.99 | 35.42 ± 5.41 |
F | 153.45 ± 20.00 | 141.50 ± 18.49 | 104.48 ± 5.39 | 51.17 ± 3.55 | 50.03 ± 6.28 | 45.79 ± 3.72 | 45.37 ± 4.07 | 40.33 ± 7.78 | 34.59 ± 5.07 | 24.84 ± 4.82 | |
Ovary | F | 125.65 ± 10.41 | 112.05 ± 9.07 | 65.38 ± 7.16 | 23.33 ± 5.35 | 21.81 ± 9.79 | 11.94 ± 4.35 | 13.23 ± 10.78 | 4.52 ± 2.23 | 5.59 ± 2.04 | 7.75 ± 6.02 |
Uterus | F | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
Vagina | F | 59.78 ± 44.38 | 81.76 ± 20.51 | 46.22 ± 20.13 | 26.01 ± 11.67 | 14.19 ± 3.99 | 8.09 ± 1.993-b | 8.51 ± 1.93 | 8.65 ± 10.82 | 8.27 ± 9.81 | 8.13 ± 8.76 |
Testes | M | 26.25 ± 2.74 | 24.94 ± 1.01 | 24.06 ± 1.10 | 7.81 ± 0.45 | 3.73 ± 0.39 | 1.83 ± 0.45 | 1.26 ± 0.09 | 1.53 ± 0.39 | 1.20 ± 0.39 | 0.87 ± 0.10 |