Proton on Carbon | Proton Chemical Shift in Standard Carboxylic Acid Metabolite M-2 | Proton Chemical Shift in Metabolite M-1 |
---|---|---|
ppm | ||
4 | 7.06 | 7.09 |
7 and 11 | 7.51 | 7.51 |
8 and 10 | 7.95 | 7.96 |
21 and 25 | 7.41 | 7.45 |
22 and 24 | 8.00 | 8.10 |
Glucuronide formation causes significant shifts of the signals of the protons on C-21 and =25 and C-22 and =24.