IC50 values of HIV protease inhibitors inhibiting [14C]TEA uptake in hOCT1 DNA-transfected HeLa cells
| Compounds | IC50 | n |
|---|---|---|
| μM | ||
| Indinavir | 61.7 ± 18.4 | 0.59 ± 0.10 |
| Nelfinavir | 21.8 ± 5.4 | 0.68 ± 0.12 |
| Ritonavir | 5.18 ± 1.21 | 0.95 ± 0.17 |
| Saquinavir | 8.26 ± 1.64 | 0.70 ± 0.09 |
IC50 and n values were obtained by fitting data from two to four separate experiments (e.g., Fig. 2) as described inMaterials and Methods, and are presented as means ± S.D.