Cumulative elimination of radioactivity associated with [3H]NTPC, [3H]NPPC, 99mTc-NTPC, and NPPC, and 99mTc-NTP 15-5 after i.v. administration to rats
| Time after Dosing | [3H]NTPC | [3H]NPPC | 99mTc-NTPC | 99mTc-NPPC | 99mTc-TP 15-5 | |
|---|---|---|---|---|---|---|
| 0–24 h | Urine | 68.54 ± 8.45 | 70.28 ± 12.15 | 62.43 ± 5.12 | 63.25 ± 4.56 | 67.57 ± 7.51 |
| Feces | 1.25 ± 0.52 | 1.32 ± 0.41 | 1.54 ± 0.31 | 1.44 ± 0.30 | 1.28 ± 0.20 | |
| 0–48 h | Urine | 82.17 ± 7.71 | 84.51 ± 6.42 | 70.57 ± 6.59 | 72.23 ± 6.45 | 78.42 ± 5.69 |
| Feces | 1.82 ± 0.21 | 1.95 ± 0.23 | 2.05 ± 0.36 | 2.21 ± 0.31 | 1.87 ± 0.28 | |
| 0–72 h | Urine | 87.58 ± 8.59 | 90.15 ± 10.21 | N.D. | N.D. | N.D. |
| Feces | 2.55 ± 0.28 | 2.82 ± 0.32 | N.D. | N.D. | N.D. |
Values, given in percentage of the administered dose, are the mean of five animals ± S.D.
N.D. = not determined.