Table 2

Pharmacokinetic parameters of moxonidine, plasma, and whole blood radioactivity (expressed as moxonidine equivalents) in Fischer 344 rats after oral administration of 0.3 mg/kg of [¹⁴C]moxonidine

	AUC_{0 to t}^2-a	C_max	T_max	T_1/2(α)	T_1/2(β)
	ng · h/ml or ng-Eq; h/ml)	ng/ml or ng-Eq/ml	h	h	h
Plasma moxonidine	4.8	4.0	0.25	1.1	NC
Plasma radioactivity	345.9	68.4	0.5	1.6	50.0
Whole blood radioactivity	376.3	102.6	0.5	1.5	32.7

NC, not calculated.
↵2-a T = 6 h for plasma moxonidine, andT = 48 h for plasma and whole blood radioactivity.