Table 4

Mean (±S.E.) cumulative elimination of radioactivity from male Fischer 344 rats after a single oral dose of 5 mg/kg of [14C]moxonidine

hNPercentage of Dose (±S.E.M)
UrineFecesCarcassCage WashTotal
12355.00  ± 6.5955.00  ± 6.59
24358.22  ± 4.7936.37  ± 1.9694.59  ± 2.85
48358.89  ± 4.4637.93  ± 2.6796.82  ± 1.79
72359.08  ± 4.4838.20  ± 2.6497.28  ± 1.84
96359.35  ± 4.3238.32  ± 2.6597.66  ± 1.68
120359.46  ± 4.2938.40  ± 2.650.37  ± 0.042.02  ± 0.68100.25  ± 1.19