Table 3

The Ki values for the inhibition of tolbutamide metabolism by various sulfonamides in recombinant CYP2C9 (Lot 27)

Ki
μM
Sulfaphenazole0.669  (0.057)
Sulfadiazine70.5  (7.7)
Sulfamethizole64.3  (4.4)
  • Numbers in parentheses represent the S.E.s of the mean values.