Pharmacokinetic parameters for GI transit and extent of absorption (Fai) of NMT in each segment
| Parameter | Stomach | Duodenum | Upper Jejunum | Lower Jejunum | Upper Ileum | Lower Ileum | Cecum |
|---|---|---|---|---|---|---|---|
| AUCra(% · h) | 46.827 | 3.409 | 5.232 | 16.953 | 31.867 | 22.623 | 16.902 |
| MRT (h) | 0.467 | 0.503 | 0.557 | 0.736 | 1.175 | 1.732 | 2.597 |
| VRT (h2) | 0.216 | 0.217 | 0.219 | 0.250 | 0.424 | 0.626 | 0.700 |
| Fai(%) | 4.917 | 4.995 | 6.870 | 23.480 | 34.129 | 25.655 | 4.919 |
Calculations were carried out from 0 to 4 h by using the data obtained by simulation studies.