Table 7

Pharmacokinetic parameters of IBN (I) and 2-MIBN (II) for the rat after an i.v. administration of 4 mg/kg

CompoundsCLtotal7-aVdsst1/2AUC7-b
ml/min/kg l/kg min μM · h
IBN46.12.5167.43.21
2-MIBN37.91.7938.14.33

Data are presented as the average value from two rats.

  • ↵7-a CLtotal, total clearance.

  • ↵7-b AUC, area under the curve.