Percentage of total recovered radioactivity as oseltamivir and metabolites in pooled 24-h urine, and 1-h plasma, liver, and lung samples after oral administration of [2-acetyl-14C]oseltamivir to rats
| Sample | Oseltamivir | GS4071 | M1 | M2 | M3 | M4 | M5 |
|---|---|---|---|---|---|---|---|
| Urine | 15.50 | 47.00 | 7.47 | 6.02 | 22.10 | 1.34 | 0.66 |
| Plasma | 0.00 | 56.50 | 8.90 | 7.00 | 24.70 | 0.00 | 0.50 |
| Liver | 0.00 | 32.50 | 15.50 | 13.40 | 24.20 | 3.80 | 2.50 |
| Lung | 37.40 | 36.10 | 0.00 | 0.00 | 13.70 | 3.00 | 9.56 |