Clearance Model | PSout3-a | Ess,HAHV3-b |
---|---|---|
ml/min | ||
Well stirred model | 1.93 | 0.527 |
Dispersion model | 9.19 | 0.441 |
Parallel-tube model | 15.5 | 0.387 |
↵3-a PSout was calculated from eqs. 1to 4 based on Ess,HAPV of 0.77 from Pang et al. (1991), the PSin and CLint,livertotal and other parameters shown in Table 2.
↵3-b Ess,HAHV was estimated according to eqs. 1to 4, based on PSin, CLint,livertotal, the estimated PSout, and other parameters shown in Table 2.