Table 3

Calculated clearances for the well-stirred, parallel tube, and dispersion models

Clearance ModelPSout3-aEss,HAHV3-b
ml/min
Well stirred model1.930.527
Dispersion model9.190.441
Parallel-tube model15.50.387
  • 3-a PSout was calculated from eqs. 1to 4 based on Ess,HAPV of 0.77 from Pang et al. (1991), the PSin and CLint,livertotal and other parameters shown in Table 2.

  • 3-b Ess,HAHV was estimated according to eqs. 1to 4, based on PSin, CLint,livertotal, the estimated PSout, and other parameters shown in Table 2.