Excretion of radioactivity (percentage of dose) over 21 days after a single administration of [14C]rosiglitazone
| Sample | Subject 1 | Subject 2 | Subject 3 | Subject 4 | Mean (S.D.) | Excluding Subject 2 |
|---|---|---|---|---|---|---|
| Oral dose (8-mg) | ||||||
| Urine | 67.6 | 53.9 | 58.0 | 69.6 | 62.3 | 65.0 |
| (7.5) | (6.2) | |||||
| Feces | 28.1 | 12.2 | 22.2 | 23.9 | 21.6 | 24.7 |
| (6.7) | (3.0) | |||||
| Total | 95.6 | 66.1 | 80.22-150 | 93.5 | 83.8 | 89.8 |
| (13.7) | (8.4) | |||||
| i.v. dose (2-mg) | ||||||
| Urine | 66.5 | 57.4 | 67.9 | 73.4 | 66.3 | 69.2 |
| (6.6) | (3.6) | |||||
| Feces | 28.3 | 26.5 | 27.6 | 18.3 | 25.2 | 24.7 |
| (4.6) | (5.6) | |||||
| Total | 94.8 | 83.9 | 95.5 | 91.62-160 | 91.4 | 94.0 |
| (5.3) | (2.1) |