Irreversibility of P450 2B1 and 2B6 inactivation by PPP
| Sample | % Activity Remaining | |
|---|---|---|
| Control | Inactivated | |
| P450 2B1 | ||
| Before dialysis | 100 | 35 ± 1 |
| After dialysis | 100 | 40 ± 11 |
| After dialysis and fresh reductase added | 100 | 38 ± 2 |
| P450 2B6 | ||
| Before dialysis | 100 | 16 ± 3 |
| After dialysis | 100 | 26 ± 1 |
| After dialysis and fresh reductase added | 100 | 30 ± 1 |
Assay conditions were as described in Experimental Procedures. The data shown represent averages from two experiments.