Table 1

Signals (arbitrary units) obtained from the DNA arrays for the various CYP enzymes

Gene	Controls (n = 10)		MS Baseline (n = 10)		MS Post-IFN (n = 10)		P Value
Gene	Mean	CV	Mean	CV	Mean	CV	Disease Effect	IFN Effect
		%		%		%
CYP 4A11	6.5 × 10³	22	5.8 × 10³	23	6.7 × 10³	24	.24	.067
CYP 2J2	2.1 × 10³	18	2.4 × 10³	22	2.6 × 10³	27	.24	.14
CYP 2E1	1.4 × 10³	75	1.8 × 10³	59	1.7 × 10³	52	.30	.16
CYP 27	1.1 × 10³	62	1.2 × 10³	81	8.3 × 10²	58	.80	.066
CYP 21	9.0 × 10²	66	7.9 × 10²	106	6.4 × 10²	82	.72	.23
CYP 2A6	8.2 × 10²	114	4.5 × 10²	79	3.8 × 10²	61	.34	.44
CYP 1A1	6.3 × 10²	47	7.6 × 10²	81	6.2 × 10²	52	.55	.23
CYP 2B6	4.1 × 10²	55	3.7 × 10²	67	3.6 × 10²	70	.73	.87
CYP 4B1	4.1 × 10²	89	3.5 × 10²	112	3.2 × 10²	102	.75	.35
CYP 27	3.5 × 10²	46	3.8 × 10²	67	3.0 × 10²	56	.85	.089
CYP 17	3.5 × 10²	36	3.9 × 10²	58	3.4 × 10²	46	.70	.22
CYP2C8	2.7 × 10²	70	2.1 × 10²	19	2.0 × 10²	29	.36	.47
CYP 3A5	2.7 × 10²	30	2.9 × 10²	46	3.1 × 10²	39	.59	.72
CYP 1B1	3.6 × 10²	45	3.3 × 10²	37	2.9 × 10²	48	.57	.48
CYP 2C9	3.2 × 10²	58	3.3 × 10²	68	3.1 × 10²	45	.85	.47
CYP19	1.3 × 10²	22	1.3 × 10²	41	1.2 × 10²	25	.82	.83