Regions | Km | ||
---|---|---|---|
2 months | 12 months | 24 months | |
μmol/μmol/l | |||
Midbrain | 30.5 ± 5.99 | 22.4 ± 7.7 | 141.1 ± 2.61-a 1-b |
Pons | 97.6 ± 12.921-c | 38.2 ± 4.7 | 126.0 ± 10.81-d |
Medulla | 124.3 ± 8.421-e | 56.3 ± 0.1 | 95.6 ± 33 |
Values of mean Km ± S.D. were obtained for midbrain, pons, and medulla of different age groups (2, 12, and 24 month) rats from the Lineweaver-Burk plot as described underExperimental Procedures. Data were analyzed by ANOVA.