Plasma clearance calculated from the elimination of unchanged drug after incubation of 125I-pamiteplase or 125I-rwt-PA with rat plasma
Each value represents mean of three experiments.
↵3-a kel calculated by one-exponential model.
↵3-b Ref. 14.
↵3-c CLplasma =kel × (plasma volume).
↵3-d CLtotal quoted from Table1.