Table 1

Comparison of plasma NOx levels and urinary excretion of trimethylamine N-oxide and ranitidine N-oxide between healthy volunteers and CVH patients

Healthy Volunteers (n= 12)CVH Patients (n = 22)
Plasma NOx (μM)26.6  ± 5.456.2  ± 26.51-150
TMA (μmol/h)88.7  ± 14.2150.3  ± 179.21-150
TMAO (μmol/h)1978.0  ± 182.2366.4  ± 252.11-150
% TMAO95.7  ± 0.573.6  ± 2.41-150
RANO (μg/ml urine)9.42  ± 1.042.22  ± 0.151-150
RA (μg/ml urine)45.63  ± 7.6127.10  ± 2.271-150
% RANO20.01  ± 2.708.27  ± 0.701-150
  • 1-150P < 0.01.