CYP Isoform | [d3]Ezlopitant Ratio | [d4]Ezlopitant Corrected Ratio5-a |
---|---|---|
CYP3A4 | 1.15 ± 0.03 | 1.13 ± 0.02 |
CYP2D6 | 1.15 ± 0.03 | 1.13 ± 0.02 |
Each value represents the mean ± S.D. of n = 6 determinations.
↵5-a Ratio corrected for statistics of two deuterium atoms per one hydrogen atom present on each 1° position of [d4]ezlopitant.