Table 1

Excretion of radioactivity after intravenous administration of [14C]AMS (11 mg/kg) to male F-344 rats (n = 4)

End of Collection PeriodCumulative Percentage of Dose Recovered in
UrineFecesBreath VolatilesCO2Total
h
634.1  ± 3.90.05  ± 0.072.01  ± 0.760.007  ± 0.00336.1  ± 4.4
1253.0  ± 7.32.08  ± 0.770.010  ± 0.00455.1  ± 8.0
2476.4  ± 2.11.20  ± 0.332.14  ± 0.780.013  ± 0.00379.8  ± 2.7
4884.9  ± 1.61.78  ± 0.722.15  ± 0.780.020  ± 0.00988.9  ± 0.7
721-a 86.2  ± 1.41.88  ± 0.732.16  ± 0.780.024  ± 0.00890.3  ± 0.4
  • F-344, Fischer 344.

  • 1-a  Includes cage rinse.