Tissue distribution of radioactivity 72 h after intravenous administration of [14C]AMS (11 mg/kg) to male F-344 rats (n = 4)
| Tissue | ng-Eq AMS per g Tissue | Tissue/Blood Ratio | Percentage of Dose in Total Tissue |
|---|---|---|---|
| Adipose | 25.3 ± 2.7 | 1.75 ± 0.74 | 0.0170 ± 0.0020 |
| Bladder | 95.3 ± 96.6 | 7.47 ± 9.69 | 0.000630 ± 0.000597 |
| Blood | 16.4 ± 6.7 | Unity | 0.00811 ± 0.00315 |
| Brain | 4.53 ± 0.94 | 0.319 ± 0.160 | 0.000298 ± 0.000050 |
| Heart | 73.2 ± 21.9 | 4.74 ± 1.51 | 0.00203 ± 0.00060 |
| Kidney | 160 ± 52 | 11.6 ± 6.1 | 0.0113 ± 0.0039 |
| Liver | 72.8 ± 14.2 | 4.85 ± 1.78 | 0.0304 ± 0.0039 |
| Lung | 87.7 ± 36.7 | 6.11 ± 3.24 | 0.00608 ± 0.00272 |
| Muscle | 4.50 ± 1.05 | 0.310 ± 0.150 | 0.0205 ± 0.0041 |
| Skin | 55.4 ± 26.4 | 4.09 ± 3.15 | 0.0892 ± 0.0406 |
| Spleen | 233 ± 81 | 16.6 ± 8.1 | 0.00616 ± 0.00243 |
| Testis | 4.49 ± 0.56 | 0.310 ± 0.134 | 0.000454 ± 0.00006 |
| Stomach3-a | 0.00234 ± 0.00104 | ||
| Small intestine3-a | 0.0479 ± 0.0145 | ||
| Cecum3-a | 0.0219 ± 0.0092 | ||
| Large intestine3-a | 0.00843 ± 0.00318 | ||
| Total | 0.276 ± 0.074 |
F-344, Fischer 344.
↵3-a Includes lumenal contents.