Table 4

1,8-Cineole 2-hydroxylation activities by recombinant human P450 enzymes

P4501,8-Cineole 2-Hydroxylation
nmol/min/nmol P450
CYP1A1<0.05
CYP1A2<0.05
CYP2A61.4
CYP2B62.3
CYP2C9<0.05
CYP2C19<0.05
CYP2D6<0.05
CYP2E1<0.05
CYP3A459.6
CYP3A514.8

1,8-Cineole 2-hydroxylation activities by recombinant P450 enzymes were determined as described under Materials and Methods. Data are means of duplicate determinations.