Morning spot urinary ratios of 6β-hydroxycortisol to free cortisol
| Subject | Cortisol | 6βOHF | 6βOHF/Cortisol Ratio | Known Alcohol, Cigarette, or Drug Coadministration | Genotype | Amino Acid Changes |
|---|---|---|---|---|---|---|
| nM | ||||||
| E5-30 | 172 | 435 | 2.53 | Nonsmoker, no alcohol, ketoconazole | A/G13989 | I118V |
| E5-72 | 156 | 391 | 2.51 | Nonsmoker, no alcohol, naproxen, cephalexin, loratadine | A/G13989 | I118V |
| E5-U55 | 86 | 210 | 2.40 | Estazolam, trazodone, baclon, antacids, ketoprofen, imipramine, digoxin, warfarin | A/G13989 | I118V |
| E7-37 | 204-a | 82 | 3.99 | Smoker, no alcohol | C/G15820 | P218R |
| E7-U86 | 112 | 268 | 2.40 | Biocal, nabumetone, fludiazepam, antacids, nefidipine, captopril | C/G15820 | P218R |
| E9-35 | 226 | 198 | 0.88 | Nonsmoker, no alcohol | A17776Insertion/wt | |
wt, wild type.
↵4-a CV > 20%.